Mutagens in Food by Hayatsu Veikko
Author:Hayatsu, Veikko [Hayatsu, Veikko]
Language: eng
Format: epub
Publisher: CRC Press
Published: 2018-05-03T16:00:00+00:00
Chapter 7.2
METABOLIC FATE OF HETEROCYCLIC AMINES FROM COOKED FOOD
Jan Alexander and Håkan Wallin
TABLE OF CONTENTS
I.
Introduction
II.
Uptake and Distribution
III.
Metabolism
A.
Metabolic Activation
B.
Esterification of the N-Hydroxy Derivative
C.
Adduct Formation In Vivo
D.
Conjugation Reactions
E.
Detoxification
F.
P-450 Induction by Heterocyclic Amines
IV.
Excretion Pathways
A.
Sex Differences
V.
Concluding Remarks
Acknowledgments
References
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